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If On-Access Scanning is enabled, saving files on Citrix XenApp and XenDesktop servers fails with an error
Technical Articles ID:   KB89870
Last Modified:  10/12/2017

Environment

McAfee Endpoint Security (ENS) Threat Prevention 10.5.x
Citrix XenApp 7.x
Citrix XenDesktop 7.x

Problem

The following issues can occur if ENS Threat Prevention 10.5.x is enabled on Citrix XenApp 7.x and XenDesktop 7.x servers:
  • You cannot save files on fat clients from the Citrix XenApp server; it fails with the following error message. However, when On-Access Scanning is deactivated, saving is possible:
     
    INVALID HANDLE
     
  • You cannot copy files from Citrix Terminal Server to the local Desktop; the process fails.
  • You cannot copy files on mapped client drives using Citrix ICA technology.

Solution

The solution for this behavior is provided by Citrix.

CAUTION: This article contains information about opening or modifying the registry.
  • The following information is intended for System Administrators. Registry modifications are irreversible and could cause system failure if done incorrectly.
  • Before proceeding, Technical Support strongly recommends that you back up your registry and understand the restore process. For more information, see: http://support.microsoft.com/kb/256986.
  • Do not run a REG file that is not confirmed to be a genuine registry import file.

Add or modify the following Windows registry key on the Citrix XenApp 7.x / XenDesktop 7.x server:
 
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\services\picadm\Parameters 
Name: EnableSophosAVSupport 
Type: REG_DWORD 
Data: 1

For more information, see https://support.citrix.com/article/CTX208125.

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