Recent updates to this article 

Date	Update
February 14, 2022	Removed the End of Life ENS 10.5.x category.

McAfee Enterprise is one of several antimalware vendors who encountered issues after installing Microsoft Windows April 2019 updates or later on systems.

Examples of reported issues include:

• Slow boot times
• Slow performance

See the following table for the latest information about each product.
 

Microsoft Windows Operating System	Microsoft KB	Endpoint Security Impact	Host Intrusion Prevention Impact	VirusScan Enterprise Impact	VirusScan Enterprise with Threat Intelligence Exchange Impact	MVISION Endpoint Impact
Windows 7 Service Pack 1	4493472 4493448	Impacted – See KB91465	Impacted – See KB91466	No impact	Impacted – See KB91467	Unsupported platform
Windows 8.1	4493446 4493467	Impacted – See KB91465	Impacted – See KB91466	No impact	Impacted – See KB91467	Unsupported platform
Windows Embedded 8 Standard	4493450 4493451	No impact	No impact	No impact	No impact	Unsupported platform
Windows 10		No impact	No impact	No impact	No impact	No impact
Windows Server 2008 R2 Service Pack 1	4493472 4493448	Impacted – See KB91465	Impacted – See KB91466	No impact	Impacted – See KB91467	Unsupported platform
Windows Server 2012 R2	4493446 4493467 4493450 4493451	No impact	No impact	No impact	No impact	Unsupported platform
Windows Server 2016	4493470	No impact	No impact	No impact	No impact	Unsupported platform
Windows Server 2019	4493509	No impact	No impact	No impact	No impact	Unsupported platform

 
For details about the fix for Client Server Runtime Subsystem (CSRSS) included in the Windows April 2019 updates, see this Microsoft article on CVE-2019-0735.